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2026 International Expert Consensus Recommendations on Image-Guided Ablation for Colorectal Liver Metastases

Year: 2026
Type: article
Abstract: Image-guided ablation has emerged as a potentially curative treatment for colorectal cancer liver metastases (CRLM), yet substantial heterogeneity persists in patient selection, technical execution, and perioperative management. To establish standardized, evidence-based guidance, a multidisciplinary panel of 68 experts including image-guided interventionalists, surgeons, and oncologists conducted a systematic review of literature from 2000 to 2025 and developed consensus recommendations through a modified two-round Delphi process. Evidence was graded using the Oxford Centre for Evidence-Based Medicine framework, achieving at least conditional consensus (≥75% agreement) for all statements. Finally, twenty consensus recommendations were established addressing patient selection, imaging evaluation, image-guided techniques, ablation strategies, complication management, surveillance protocols, and combination therapies. This expert consensus provides a comprehensive framework for optimizing image-guided ablation as an integral component of multidisciplinary, personalized CRLM management.
Source: Liver Cancer
Institutions: Sun Yat-sen University, Sixth Affiliated Hospital of Sun Yat-sen University, Kindai University, Seoul National University, Seoul National University Hospital, Humanitas University, IRCCS Humanitas Research Hospital, Juntendo University, Zealand University Hospital Køge, University of Copenhagen, Copenhagen Academy for Medical Education and Simulation, IRCCS Azienda Ospedliero-Universitaria di Bologna Policlinico di Sant'Orsola, University of Bologna, University of Wisconsin–Madison, Samsung Medical Center, Samsung Changwon Hospital, Sungkyunkwan University, University Hospital Frankfurt, Chinese PLA General Hospital, Chinese People's Liberation Army, Second Hospital of Hebei Medical University, Zhejiang University, Sun Yat-sen University Cancer Center, Fudan University, Zhongshan Hospital, Tianjin Third Central Hospital, Peking University Cancer Hospital, Third Affiliated Hospital of Harbin Medical University, Kunming Medical University, Tongji Hospital, Huazhong University of Science and Technology, National Taiwan University Hospital, Second Affiliated Hospital of Zhejiang University, Università Cattolica del Sacro Cuore, Agostino Gemelli University Polyclinic, Istituti di Ricovero e Cura a Carattere Scientifico, Third Affiliated Hospital of Sun Yat-sen University, Henan Cancer Hospital, Shanxi Medical University, First Hospital of Shanxi Medical University, Jilin University, Chinese Academy of Medical Sciences & Peking Union Medical College, West China Medical Center of Sichuan University, Peking Union Medical College Hospital, West China Hospital of Sichuan University, Xi'an Jiaotong University, First Affiliated Hospital of GuangXi Medical University, China-Japan Friendship Hospital, Tongji University, Shanghai Tenth People's Hospital, First Hospital of Jilin University, Affiliated Hospital of Qingdao University
Language: English
Subfield: Hepatology
Field: Medicine
Open Access status: gold
Estimated APC paid: $3,590
OpenAlex ID: W7223977950
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