Work

Reconstructing the irradiated urethra: Double-Faced buccal mucosal graft urethroplasty after treatment of primary urethral cancer

Year: 2026

Type: article

Abstract: We report the case of a 42-year-old man who developed a 6 cm near-obliterative bulbar and membranous urethral stricture after radiation for primary urethral squamous cell carcinoma. Reconstruction was performed using a combination of membranous scar excision and a double-faced buccal mucosal graft urethroplasty. Cystourethroscopy at 4 months demonstrated a widely patent urethra, and the AUA Symptom Score improved from 25 before surgery to 3 at three years. Urethroplasty after radiation for urethral cancer has not been previously well described. This case suggests single-stage urethroplasty is a feasible option for reconstruction of urethral strictures after radiation for urethral cancer.

Source: Urology Case Reports

DOI: 10.1016/j.eucr.2026.103653

Authors: Negar Behtash, Sikai Song, Zhina Sadeghi, Keith Rourke, Joel Gelman

Institution: University of California, Irvine

Language: English

Topic: Urological Disorders and Treatments

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,160