Work

New thiazole/coumarin hybrids as EGFR inhibitors with potential VEGFR-2 inhibition (design, synthesis, biological evaluation, and dynamic stimulation)

Year: 2026

Type: article

Abstract: values of 0.14, 0.27, 0.378, and 2.94 µM, respectively. Furthermore, every pairwise separation exceeded twice the block-averaged standard error. Compound 6a was identified as the lead compound of the series.

Source: RSC Advances

DOI: 10.1039/d6ra07747a

Authors: Sara Waheed Elshemy, Taha F. S. Ali, Ahmed M. Sayed, Samar H. Abbas

Institutions: Minia University, Almaaqal University

Language: English

Topic: Heterocyclic Compound Synthesis and Bioactivity

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,042

Funder: National Cancer Institute

OpenAlex ID: W7224079643

FWCI:

Cites: 48

Cited by:

Related to: 10