Work

Alzheimer’s disease research must connect vascular molecular phenotypes with physiology

Year: 2026

Type: article

Abstract: Molecular profiling studies have mapped vascular alterations in Alzheimer's disease, but have not proven a role for them in pathology. Longitudinal studies are needed to link molecular and structural changes to vascular mechanics, hemodynamics, and tissue perfusion.

Source: PLoS Biology

DOI: 10.1371/journal.pbio.3004051

Authors: Thomas S. Lewis, Jessica Wagner, Jonas J. Neher

Institutions: German Center for Neurodegenerative Diseases, German Center for Neurodegenerative Diseases (DZNE) Dresden, Ludwig-Maximilians-Universität München, Munich Cluster for Systems Neurology, University of Tübingen

Language: English

Topic: Alzheimer's disease research and treatments

Subfield: Physiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $5,500