Year: 2026
Type: article
Study design: Case Report
Abstract: Psoriasis is a chronic immune-mediated disease, in which oral involvement is uncommon and frequently overlooked.We report a 38-year-old man with no personal or family history of psoriasis who presented with chronic, recurrent erythematous depapillation of the left hemi-tongue, and unresponsive to prolonged antifungal therapy.Dermoscopy showed regularly distributed dotted vessels over hypertrophic papillae, contrasting with the normal contralateral mucosa, and guided a targeted punch biopsy.Histology demonstrated psoriasiform epithelial hyperplasia with parakeratosis, elongated rete ridges, and dilated tortuous capillaries within the lamina propria and Munro microabscesses; periodic acid-Schiff staining excluded fungal infection.Extension work-up disclosed no cutaneous, scalp, nail, or joint involvement, supporting exclusive lingual psoriasis.Topical clobetasol propionate produced marked improvement within 4 weeks, with no relapse after 1 year of follow-up.This case illustrates the value of dermoscopy in recognizing atypical oral psoriasis and in avoiding prolonged ineffective antifungal treatment.
Language: English
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: diamond
OpenAlex ID: W7224086584