Salvage Subtotal Supracricoid Laryngectomy with Cricohyoidoepiglottopexy for Late Recurrence of Irradiated T1a Glottic Carcinoma Eighteen Years After Radiotherapy: A Case Report and Literature Review
Year: 2026
Type: article
Study design: Case Report
Abstract: Early glottic carcinoma treated with radiotherapy has excellent local control, but a minority of patients develop recurrence, which classically occurs within the first three years. Late recurrences are uncommon and pose specific diagnostic and therapeutic challenges in a previously irradiated larynx. We report the case of a 72-year-old man with a history of T1aN0M0 glottic squamous cell carcinoma treated with 32 fractions of radiotherapy (completed in 2008) and endoscopic resection of a local lesion in 2014, who presented after a 12-year disease-free interval with progressive dysphonia. Endoscopy revealed a 15-mm polypoid, hypervascular lesion on the anterior and middle thirds of the left vocal fold, sparing the anterior commissure, posterior third, ventricle and subglottis. Biopsy showed a high-grade intraepithelial lesion with post-radiation changes, and computed tomography and neck ultrasound showed no deep invasion or cervical disease. The patient underwent salvage subtotal supracricoid laryngectomy with cricohyoidoepiglottopexy (SSC-CHEP) with 20 mL of blood loss, no intraoperative complications and grossly negative margins. The postoperative course was favorable, and he was discharged with the drain in place for outpatient follow-up, with good postoperative evolution; definitive histopathology is pending. This case, together with a brief review of the literature, supports SSC-CHEP as an oncologically sound, larynx-preserving alternative to total laryngectomy for carefully selected radiorecurrent glottic tumors, even after very long disease-free intervals and in older patients with good functional status.
Authors: Miguel Angel Bautista Badal, Jose Francisco Gallegos Hernandez, Genaro Alejandro Trujillo Franco, Randall Cruz- Soto, José Alfredo Calderón Anguiano, Cristian Yair Morales Manzo, Yadira Margarita Arias Pérez, Sara Cruz Vergara, Paola Esperanza De La Cruz Medina, José David Rodríguez Enríquez
Language: English
Topic: Head and Neck Cancer Studies
Subfield: Otorhinolaryngology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7224105107