T cell–mediated depletion of intratumoral regulatory T cells using a CCR8xCD3 T cell–engaging bispecific antibody (TCB) promotes antitumor immunity in preclinical mouse models
Year: 2026
Type: article
Source: Science Translational Medicine
Authors: Baomei Wang, Isabel Ishizuka, Emel Esen, Ji Li, Cecilia Chiu, Yonglian Sun, Zhonghua Lin, Dhaya Seshasayee, Aija Kusi, Yu Zhong, Wendy Halpern, Adeyemi O. Adedeji, Lanlan Yu, Peter Tran, Zhaojun Yin, Shang-Fan Yu, Geoff Del Rosario, Yoko Oei, Yagai Yang, Jill Schartner, Mary Ann Go, Giulia Protti, Soren Muller, Cong Wu, Ran Li, Genee Lee, James T. Koerber, Sascha Rutz, Teemu T. Junttila
Institution: Genentech
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
OpenAlex ID: W7224122290