Management of Obesity in Special Populations and Limited-Resource Settings: An Egyptian Medical Position Statement
Year: 2026
Type: article
Abstract: Background: Obesity/adiposity-based chronic disease is a chronic progressive relapsing disease linked to several comorbidities, with rising prevalence in Egypt. Limited local guidelines and healthcare challenges necessitate evidence-based, culturally adapted strategies. Methods: The Egyptian Medical Association for the Study of Obesity convened a clinical multidisciplinary panel to develop consensus recommendations. Evidence was synthesized from literature, prioritizing resource-limited settings and special situations. Result: Assessment: Move beyond Body Mass Index to include waist circumference, waist/height ratio, body composition, and screening for obesity-related complications and diseases. Lifestyle Interventions: a-Nutrition: Mediterranean/dietary approach to stop hypertension diets, slow eating, and supervised fasting (eg Ramadan and Christian). b-Activity: Culturally tailored approaches (eg prayer-time movement and Arabic apps). c-Behavior: Cognitive-behavioral therapy and family-inclusive support. Pharmacotherapy: Use of approved agents (orlistat, naltrexone/bupropion, liraglutide, semaglutide, and tirzepatide) according to obesity-related complications and diseases and age group. Avoid GLP-1, GLP-1/GIP analogues in patients with medullary thyroid cancer, and all agents during pregnancy. Bariatric Surgery: Indicated for body mass index ≥ 40 kg/m 2 (or ≥ 35 with obesity-related complications and diseases), with lifelong micronutrient supplementation. Special Populations: a-Adolescents: Focus on growth, not only weight-loss; consider pharmacotherapy in different age groups. b-Elderly: Prioritize muscle preservation; avoid weight loss unless obesity-related complications and diseases exist. c-Pregnancy: No weight loss; delay postpartum interventions until lactation is established. Policy Actions: Mandate food labeling, tax sugar-sweetened beverages, and integrate obesity services into primary healthcare. Conclusion: These recommendations provide a pragmatic framework for obesity/adiposity-based chronic disease management in Egypt, emphasizing affordable, patient-centered care, and clinical multidisciplinary collaboration and policy support. Keywords: obesity, Egypt, limited resources, guidelines, EMASO
DOI: 10.2147/dmso.s629991
Authors: Mona A Hegazy, Amr Mattar, Maissa Mohamed Shawky, Dina Soliman, Maha Mowafy, Yasmine Mohamed NourEldin, Ahmed Madbouli Noweir, Mohamed Kamal Aboulghate, Mostafa Elshazli, May AbdelMoneim Hassaballa, Shereen Abdelghaffar, Heba Morad Bahgat, Noha Sabry, Hesham Salah Eldin Taha, Inass Shaltout, Mona Yousry
Language: English
Subfield: Pharmacology (medical)
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $2,836
Funder: Novo Nordisk
OpenAlex ID: W7224136908
