Work

3-Methyl-1-phenyl-4-thioaroylpyrazolones—Synthesis, Preferred Solid-State Geometry and an Atypical Side Product of Lawesson’s Thionation

Year: 2026

Type: article

Abstract: A series of five novel 3-methyl-1-phenyl-4-(4-thioaroyl)-pyrazol-5-ones is obtained in excellent yields by thionation of the corresponding O-analogues with Lawesson’s reagent. The products are characterized in solution and solid phase. It is found that only mono-thionation occurs and that the products exist in enol-thione forms. Atypical side products are isolated and characterized. The preferred solid state forms are analyzed and compared with those of the corresponding O-analogues.

Source: Organics

DOI: 10.3390/org7040046

Authors: Vanya Kurteva, Magdalena Angelova, Rusi Rusew, Zhanina Petkova, Boris Shivachev

Institutions: Bulgarian Academy of Sciences, Institute of Mineralogy and Crystallography "Acad. Ivan Kostov" Bulgarian Academy of Sciences

Language: English

Topic: Synthesis and Reactivity of Sulfur-Containing Compounds

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,207

Funder: Bulgarian National Science Fund