Work

Postoperative Visual Quality Analysis of DFT015 Intraocular Lens Implantation in Cataract patients

Year: 2026

Type: article

Abstract: Objective: To evaluate the visual outcomes and visual quality of cataract patients after implantation of the DFT015 extended depth-of-focus (EDOF) intraocular lens (IOL), including distance, intermediate, and near visual acuity. Methods: This single-arm, observational study included 41 cataract patients (58 eyes) who underwent cataract surgery with implantation of the DFT015 IOL between October 2024 and November 2025. Uncorrected and corrected distance, intermediate, and near visual acuities were recorded at 1 day, 1 week, 3 months, and 6 months postoperatively. The functional range of vision was assessed using defocus curves; whole-eye aberrations and the modulation transfer function were measured with an OPD-Scan III; and patient-reported visual symptoms and satisfaction were assessed using the Quality of Vision questionnaire. Generalized estimating equations (GEE) accounting for the correlation between the two eyes of the same patient were used for statistical comparisons. Results: At 6 months postoperatively, uncorrected and corrected distance, intermediate, and near visual acuities improved significantly compared with preoperative values (all P < 0.001). Defocus curves showed progressive improvement over time; by 3 and 6 months, patients maintained functional vision (logMAR < 0.2) across a defocus range of -0.50 D to -2.00 D. Total and higher-order aberrations decreased progressively after surgery, reaching low and stable levels by 3 months, and modulation transfer function curves approached those of normal eyes. Only a minority of patients reported mild photic phenomena, such as glare and halos, which were well tolerated; no severe adverse visual events were observed. Conclusion: In this single-arm cohort, implantation of the DFT015 IOL was associated with improved full-range visual acuity and favorable postoperative visual quality, with a low incidence of visually significant photic phenomena. Randomized or comparative studies with appropriate control groups are warranted to confirm these findings.

Source: Clinical ophthalmology

DOI: 10.2147/opth.s642876

Authors: Yuru Li, Yong Zhang, Tinglan Huang, Peiyu Xing, Xingli Wang, Yang Zhao

Institutions: Liaoning University of Traditional Chinese Medicine, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang The Fourth Hospital of People

Language: English

Topic: Intraocular Surgery and Lenses

Subfield: Ophthalmology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,320