Year: 2026
Type: article
Study design: Case Report
Abstract: Bronchial granular cell tumor (GCT) is exceptionally rare, accounting for only 6%-10% of all GCT cases and may be misdiagnosed because of its nonspecific clinical and radiological features. We report a 50-year-old man with a 20-day history of intermittent cough, sputum production, chest tightness, and dyspnea. Chest computed tomography revealed a 12 × 11 mm nodule in the medial segmental bronchus of the right middle lobe, resulting in incomplete lung expansion. Bronchoscopy demonstrated a polypoid mass obstructing the bronchial lumen. Histopathological examination and immunohistochemical positivity for S100, SOX10, and CD68 confirmed bronchial GCT. The patient underwent video-assisted thoracoscopic right middle lobectomy, followed by an uneventful recovery, with no recurrence at three months. This case highlights the diagnostic challenges of bronchial GCT and supports surgical resection as the preferred treatment, particularly for lesions causing substantial bronchial obstruction.
Source: Journal of Surgical Case Reports
DOI: 10.1093/jscr/rjag997
Authors: Yilun Wang, Yaojing Zhang, Hongcan Shi
Institutions: Northern Jiangsu People's Hospital, Yangzhou University
Language: English
Topic: Tumors and Oncological Cases
Subfield: Pathology and Forensic Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $1,000
OpenAlex ID: W7224744814