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Hemophagocytic Lymphohistiocytosis Secondary to Tropical Infections: A Case Series from a Tertiary Care Hospital

Year: 2026

Type: article

Abstract: Hemophagocytic lymphohistiocytosis (HLH) can be triggered by various infections, including tropical illnesses like dengue fever and scrub typhus.This series included five children with secondary HLH associated with tropical illnessess.The cohort included three girls and two boys aged 1-13 years.Two cases were associated with dengue fever and three with scrub typhus.All children met at least five of the HLH-2004 diagnostic criteria.The study underscores the importance of considering HLH in children with prolonged febrile illness in endemic regions and highlights the clinical improvement of pulse steroid therapy in such cases.

Source: Imsang soa hyeoraek jong-yang/Imsang soa hyeol'aeg jong'yang/Clinical pediatric hematology-oncology

DOI: 10.15264/cpho.2026.33.2.78

Authors: Priya Jose, Peter Prasanth Kumar K, Nishanth Rajan, Alvina Anne Roosevelt, Dhanushya Jayaprakash, CM Kiran

Institution: Pondicherry Institute of Medical Sciences

Language: English

Topic: Autoimmune and Inflammatory Disorders Research

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7224769227

FWCI:

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