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A Three-Year Surveillance Study on Post-pandemic Respiratory Pathogen Ecological Characteristics in Acute Respiratory Infections — Quanzhou City, Fujian Province, China, 2023–2026

Year: 2026
Type: article
Study design: Observational Study
Abstract: What is already known about this topic?: Post-pandemic circulation of respiratory pathogens has been reshaped, yet evidence from long-term multipathogen surveillance remains scarce. What is added by this report?: Among 7,029 cases of acute respiratory infection (ARI) in Quanzhou (2023-2026), influenza viruses and SARS-CoV-2 dominated in alternation, while common respiratory viruses co-circulated as multiple subtypes. Viral pathogens tended to be mutually exclusive, whereas bacteria were preferentially codetected. Male sex, older age, pathogen negativity, and certain monoinfections were associated with greater severity; common coinfections were not. What are the implications for public health practice?: The post-pandemic ARI landscape is a dynamic ecosystem driven jointly by viral interference and bacterial co-colonization, and it calls for sustained multipathogen surveillance.
DOI: 10.46234/ccdcw2026.220
Authors: Chen Xiaoling, Wang Changliang, Wang Weiming, Huang Jiajie, Lin Manfang, Liu Jiangyi, Yang Mengjie, Gong Caiting, Huang Xinlan, Zhang Jie, Liu Jun, Zheng Youxian
Institutions: Fujian Medical University, First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, Guangzhou Laboratory, Guangzhou Institute of Respiratory Health, Guangzhou Medical University
Language: English
Subfield: Epidemiology
Field: Medicine
Open Access status: diamond
OpenAlex ID: W7224889180
FWCI:
Cites: 8
Cited by:
Related to: 10