The impact of preoperative nutritional status on recovery of physical function after lung resection for non-small cell lung cancer
Year: 2026
Type: article
Study design: Observational Study
Abstract: [Purpose] This study examined the association between the Controlling Nutritional Status (CONUT) score, an indicator for preoperative nutritional status, and postoperative recovery of physical function after lung resection in participants with non-small cell lung cancer (NSCLC). [Participants and Methods] This study included 82 participants with NSCLC. Participants were classified into a normal group (0–1 point) and a light malnutrition group (2–4 points) based on their CONUT scores. The primary outcome was the postoperative 6-minute walk distance (6MWD), and regression analysis was performed to estimate the coefficient for the preoperative 6MWD against the light malnutrition group. [Results] Of the 82 participants, 26 had light malnutrition (31.7%). The incidence of postoperative complications was significantly higher in the light malnutrition group than in the normal group. In addition, the postoperative 6MWD and 6MWD recovery were significantly lower in the light malnutrition group. In regression analysis preoperative light malnutrition was associated with postoperative 6MWD (β=−36.1; 95% confidence interval, −69.5 to −2.62). However, this association was attenuated in Model 3 after adjusting for postoperative complications. [Conclusion] Preoperative light malnutrition is associated with delayed postoperative recovery of physical function, suggesting a possible mediation pathway involving an increased risk of postoperative complications.
DOI: 10.1589/jpts.38.469
Language: English
Subfield: Pulmonary and Respiratory Medicine
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7225019627