Clinical Profile and Predisposing Conditions of Culture-Confirmed Bacteriuria Among Adult Medical Inpatients with Pyuria: A Cross-Sectional Study in Bangladesh
Year: 2026
Type: article
Study design: Observational Study
Abstract: Background: Pyuria frequently triggers urine culture in medical wards, yet the clinical presentation and host conditions underlying culture-confirmed bacteriuria among hospitalised adults in Bangladesh remain poorly characterised. Objective: To describe the clinical presentation, predisposing conditions and uropathogen profile of culture-confirmed bacteriuria among adult medical inpatients with pyuria. Methods: This descriptive cross-sectional study was conducted in the Department of Medicine, Dhaka Medical College Hospital, over six months. Of 127 adults with pyuria screened, 100 with significant bacteriuria (≥10⁵ CFU/mL) were analysed. Sociodemographic characteristics, symptom status, predisposing conditions and culture results were summarised with 95% confidence intervals (CIs). Results: Mean age was 55.1 ± 10.6 years; 78% were women and 60% belonged to low-income households. Sixty-four patients (64%) had symptomatic bacteriuria and 36 (36%) had asymptomatic bacteriuria. Diabetes mellitus was the most frequent predisposing condition (38%; 95% CI 29.1–47.8), followed by postmenopausal status (33.3% of women), urinary catheter or stent (16%) and neurological disorders (10%). Among diabetic patients, 78.9% had diabetes for more than five years and 84.2% had uncontrolled glycaemia. Seventy-six patients had one predisposing condition, 16 had two or more and eight had none. Escherichia coli accounted for 68 of 118 isolates (57.6%), followed by Pseudomonas spp. (11.9%) and Enterococcus spp. (8.5%). Polymicrobial growth (18%) clustered among diabetic and catheterised patients. Conclusion: Culture-confirmed bacteriuria among medical inpatients with pyuria was concentrated in women and in patients with diabetes, urinary devices or neurological disease, and one-third was asymptomatic. Integrating symptom and risk assessment into urine-culture interpretation could limit unnecessary antibiotic exposure.
Language: English
Subfield: Epidemiology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7225040384