Work

Identification of NSC factors.

Year: 2026

Type: preprint

Abstract: Neural stem cells have regenerative and cell type-specific properties that distinguish them from the embryonic stem cell. We used transcriptomics here for discovery of novel factors required for or associated with the survival and function of the neural stem cell. We describe a (10) factor assembly of nuclear factors that specify the neural stem cell and distinguish the NSC from the bES cell including Sox1, Sox5, Runx2, Ebf2, Tcf12, Atoh8, Dach1, Pou3f2/Pou3f3, Gbx2 and Foxo4. Zbtb16, Zmiz1, Zswim6, Znf521, Zc3h12c, and Znf436 comprised a second group of factors associated with identity of the neural stem cell.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.23891452

Author: Mamoor, Shahan

Language: English

Topic: Neurogenesis and neuroplasticity mechanisms

Subfield: Developmental Neuroscience

Field: Neuroscience

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7225082668

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Related to: 10