Work

CT-guided percutaneous lung biopsy under calm breathing

Year: 2026

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Objectives: To investigate the use of syringe needle-assisted localization to enable patients to undergo CT-guided percutaneous lung biopsy performed under calm breathing. This approach was developed to facilitate CT-guided lung biopsy in patients who have difficulty performing breath-holding maneuvers and to improve procedural feasibility under calm breathing conditions. Methods: A total of 200 patients who underwent CT-guided percutaneous lung biopsy were included and randomly allocated to either a syringe needle-assisted calm breathing group (n=100) or a conventional breath-holding group (n=100). Procedural outcomes, including puncture success rate, procedure-related complications (pneumothorax, pulmonary hemorrhage, hemothorax, chest wall hematoma, and air embolism), and the number of needle adjustments, were collected and compared between the two groups. Results: No statistically significant differences were detected in puncture success rate or complication rates. The calm breathing group showed a tendency toward fewer needle adjustments, although the statistical interpretation differed between the primary mean-based analysis and the non-parametric sensitivity analysis. Conclusions: CT-guided percutaneous lung biopsy under calm breathing with syringe needle-assisted localization was feasible in the present study and may be useful for patients who have difficulty cooperating with breath-holding instructions.

Source: Open Medicine

DOI: 10.1515/med-2026-1533