Work

Double Trouble: Myocarditis After Dual Checkpoint Inhibitors

Year: 2026

Type: article

Abstract: Immune checkpoint inhibitor (ICI)-associated myocarditis is a serious immune-related adverse event with a variable clinical presentation and challenging management.We present a case of fulminant ICI-associated myocarditis complicated by complete heart block, decompensated heart failure, and cardiogenic shock, followed by neuromuscular toxicity with myasthenia gravis overlap.Our case highlights the clinical challenges of ICI myocarditis and a possible treatment strategy involving high-dose steroids and T-cell antimetabolites.

Source: Cureus

DOI: 10.7759/cureus.118993

Authors: John C Dillon, Colin Snook, Rongras Damrongwatanasuk, Cody Bergman

Institution: University of Louisville

Language: English

Topic: Cancer Immunotherapy and Biomarkers

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7225101932