Unmasking Panic Disorder in Adults with Leukemia: A Systematic Review of Prevalence, Risk Factors, and Management
Year: 2026
Type: review
Study design: Systematic Review
Abstract: Objective: To assess prevalence, risk factors, and management of panic disorder in adult leukemia patients. Methods: A PRISMA-guided systematic search of PubMed, Embase, PsycINFO, and Cochrane Library (2015-July 20, 2025) identified studies on adults (⩾18 years) with leukemia and panic disorder or anxiety, diagnosed via DSM/ICD or validated scales (e.g., HADS-A). Data on prevalence, risk factors, and treatments were extracted. Quality was assessed using the Newcastle-Ottawa Scale. Results: Seven studies (n = 1,292) reported anxiety prevalence of 15%-39% and panic disorder at 2%-8%. Risk factors included younger age and chemotherapy. CBT and SSRIs were effective. Conclusions: Panic disorder affects leukemia patients' quality of life, necessitating routine screening.
Source: Psychopharmacology Bulletin
DOI: 10.64719/pb.21618
Author: Mridul Sarangal
Institutions: Carilion Clinic, Virginia Tech
Language: English
Topic: Cancer survivorship and care
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7225142745