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Discovery of N -Acyl Pyrimidine-Biphenyl Small-Molecule PD-L1 Inhibitors that Restore T Cell Function and Suppress Tumor Growth in Breast Cancer

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Year: 2026
Type: article
Source: ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.6c00411
Authors: Vidya Jyothi Alli, Teja Nallavolu, Maresha Ramakrishna, Bhumesh Machukuri, Karamtoth Swapnanjali, Swapnil Anil Sule, Baji Baba Shaik, Yogesh Chandra, Ramesh Ummanni, Surender Singh Jadav
Institutions: Indian Institute of Chemical Technology, Council of Scientific and Industrial Research, Academy of Scientific and Innovative Research
Language: English

Topic: Cancer Immunotherapy and Biomarkers
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Indian Council of Medical Research, Council of Scientific and Industrial Research, India, Human Resource Development Group
OpenAlex ID: W7225155875
FWCI:
Cites: 20
Cited by:
Related to: 10
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