Work

Green Synthesis of Oximes Using Low-Melting Sugar Mixtures

Year: 2026

Type: conference-paper

Abstract: Oximes are versatile nitrogen-containing compounds synthesized by condensing aldehydes or ketones with hydroxylamine. Conventional methods often involve toxic solvents, prolonged heating, and significant chemical waste. In this study, a greener oxime synthesis method was developed that uses a biodegradable, sugar-based deep eutectic solvent (DES) composed of inexpensive, non-toxic, recyclable sugars without an added catalyst. Aldoximes and ketoximes were successfully synthesized using both conventional water bath heating at 80–90 °C and microwave irradiation. While both methods afforded good yields, microwave assistance significantly reduced reaction time and energy consumption. The simple, safe, and inexpensive protocol is particularly suitable for undergraduate green chemistry laboratories and promotes sustainable synthetic practices.

DOI: 10.3390/chemproc2026022090

Authors: Sudeep Koppayithodi, Pratiksha Rajadhyaksha, Gomathi Shridhar

Institutions: Universitat Jaume I, St. Xavier's College

Language: English

Topic: Ionic liquids properties and applications

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

SDG: Responsible consumption and production

Open Access status: gold

Funder: Department of Atomic Energy, Government of India

OpenAlex ID: W7225173678

FWCI:

Cites: 16

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Related to: 10