Work

Hydrophobicity–flexibility synergy in tween micelles: kinetic modulation towards sustainable oxidation of l -leucine

Year: 2026

Type: article

Abstract: ' value (0.42 to 0.89) in SAXS analysis suggests the l-leucine induces noticeable structural organizations of the TW-80 aggregates compared to TW-20. Additionally, zeta potential and DLS measurements validated the large surface charge (-14.49 mV) and size of ∼50 nm for the 0.1 mM TW-80 micellar system, making it more stable and more dynamic. Surprisingly, the shorter average lifetime of 0.1 mM TW-80 alone (5.1 ns) and 109.63 ns in the presence of l-leucine also suggests that the probe molecule experiences a more flexible microenvironment in 0.1 mM TW-80 system. Furthermore, the proposed reaction mechanism is corroborated by thermodynamic analysis, Marcus theory, FMO analysis and spin density distribution analysis. Notably, this work presents an innovative shift toward sustainable oxidation processes by substituting conventional metal catalysts with benign surfactant-based platform for the l-leucine oxidation.

Source: RSC Advances

DOI: 10.1039/d6ra07838a