Work

Engineering AP/Exo‐Cas12 as an efficient toolbox for rice genome editing via integrated repair and exonuclease modules

Year: 2026

Type: article

Abstract: A modular apurinic/apyrimidinic (AP)/Exo-Cas12 toolbox integrates cell selection enrichment with AP-repair pathways or exonucleases for plant editing. It achieves efficient multiplex genome editing and easily detectable large DNA deletions in rice, providing a robust platform for multigene knockouts and crop improvement.

Source: Journal of Integrative Plant Biology

DOI: 10.1111/jipb.70440

Authors: Nan Chai, Ruixiang Zhang, Guangzhou Li, Liying Su, Jun Wen, Shirui Huo, Xudong Yuan, Ruyue Chang, Xinglei Zheng, Zhiye Zheng, Taoli Liu, Dongchang Zeng, Qiupeng Lin, Yao‐Guang Liu, Xianrong Xie, Jiantao Tan, Qinlong Zhu

Institutions: South China Agricultural University, Guangxi Normal University, Rice Research Institute, Guangdong Academy of Agricultural Sciences

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: bronze

OpenAlex ID: W7225191595

FWCI:

Cites: 5

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Related to: 10