Work

Tumor vessel sabotage: CD4⁺ T cells enlist macrophages

Year: 2026

Type: article

Abstract: In a recent study published in Science, Lian et al. shed light on a previously unrecognized mechanism of CD4 T cell-mediated control of tumor growth that does not require direct tumor cell recognition and can operate independently of interferon (IFN)γ, relying instead on stromal remodeling and destruction of tumor-associated vessels. 1

Source: Signal Transduction and Targeted Therapy

DOI: 10.1038/s41392-026-03019-2

Authors: Stefano Ugel, Francesco De Sanctis

Institution: University of Verona

Language: English

Topic: Immune cells in cancer

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,790