ERCP Timing Before Deterioration in Acute Cholangitis Using Bilirubin WBC Creatinine Platelets and Albumin Through a Stochastic Optimal Stopping Model
Year: 2026
Type: software
Abstract: Research code and supporting materials for a literature-parameterized mathematical proof-of-concept investigating candidate ERCP timing in acute cholangitis. The model combines nonlinear ordinary differential equations for laboratory and latent physiological states, a four-state continuous time Markov chain, competing theoretical decision cost intensities, and finite horizon optimal stopping. Numerical analyses include scenario comparisons, Latin hypercube sensitivity analysis, and stochastic initial condition perturbations. Model stopping times are illustrative computational outputs, not clinically validated treatment recommendations.
Author: Prihantini
Language: English
Subfield: Gastroenterology
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7225234634