Work

A combination of p-coumaric acid and metformin enhances the cytotoxicity of carboplatin and epirubicin in the gastric cancer cell line AGS.

Year: 2026

Type: article

Abstract: values. Collectively, these findings suggest that pCA and metformin (Met) warrant further investigation as promising therapeutic candidates for overcoming drug resistance in gastric cancer and could introduce new ways to fight against drug resistance in gastric cancer models.

Source: PubMed Central

DOI: 10.22099/mbrc.2026.56296.2311

Authors: Yousef Sefidi-Heris, Ehsan Zarei, Iraj Saadat

Institution: Shiraz University

Language: English

Topic: Metabolism, Diabetes, and Cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Shiraz University