Year: 2026
Type: article
Abstract: Fragment screening is widely used to provide useful starting points for drug discovery. There are many methods that are used today for conducting fragment-based screens. and fragment libraries vary widely in size. In this perspective, I discuss the method that I use for fragment screening and the size of my fragment library, the reasons for these choices, and provide an example that illustrates the advantages.
Source: ChemMedChem
DOI: 10.1002/cmdc.70503
Author: Stephen W. Fesik
Institution: Vanderbilt University
Language: English
Subfield: Drug Discovery
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $4,150
OpenAlex ID: W7225244456