Work

Fragment Covalent Bond Formation at SOS1 Tyr-884 Inhibits KRAS Nucleotide Exchange

Year: 2026

Type: preprint

Source: bioRxiv (Cold Spring Harbor Laboratory)

DOI: 10.64898/2026.11.01.763478

Authors: Khuchtumur Bum-Erdene, Giovanni Gonzalez-Gutierrez, Mona K Ghozayel, Samy Meroueh

Institutions: Indiana University School of Medicine, Indiana University, University of Illinois Urbana-Champaign

Language: English

Topic: Protein Kinase Regulation and GTPase Signaling

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W7225276395

Cites:

Cited by:

Related to: