Work

MDNA is a hematopoietic system-specific interferon stimulated gene.

Year: 2026

Type: preprint

Abstract: We demonstrate here selective control of the interferon-stimulated gene (ISG) MDNA in the hematopoietic compartment. MDNA was induced in cells of the blood following interferon pathway activation by IFN-alpha or following interferon pathway activation associated with viral infection. In human cells l, MDNA expression was controlled at least in part by the NLR receptor NOD2.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.23978413

Author: Mamoor, Shahan

Language: English

Topic: interferon and immune responses

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7225312040

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