Work

Discovery of Ebselen Analogs as Novel Inhibitors of Polyphosphate Metabolism to Attenuate Virulence and Show Combination Benefit with Meropenem in Pseudomonas aeruginosa

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c01419

Authors: Yingjie Wang, Zihao Zhou, Kaiqiang Fan, Jin Jin, Yingjun Zhou, Xi Lu, Zongchao Jia, Xu Deng

Institutions: Central South University, Queen's University, Chinese Academy of Medical Sciences & Peking Union Medical College

Language: English

Topic: Bacterial biofilms and quorum sensing

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Cystic Fibrosis Canada, National Natural Science Foundation of China, Hunan Provincial Science and Technology Department, Natural Science Foundation for Distinguished Young Scholars of Hunan Province

OpenAlex ID: W7225401453

FWCI:

Cites: 51

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Related to: 10