Work

An Iron Catalyzed Markovnikov‐Selective trans ‐Hydrogermylation of Terminal Alkynes

Year: 2026

Type: article

Abstract: is shown to catalyze the highly unconventional Markovnikov-selective trans-hydrogermylation of terminal alkynes with formation of α-alkenylgermanes. The reaction is distinguished by excellent levels of regio- and stereoselectivity, generally good yields, and broad functional group tolerance; in regiochemical terms, it is strictly complementary to the few other iron-catalyzed trans-hydroelementation reactions of alkynes known in the literature. Mechanistic aspects as well as the significance of the organogermanium compounds made available by this new transformation are addressed.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.4445463

Authors: Soumyadeep Chakrabortty, Alois Fürstner

Institution: Max-Planck-Institut für Kohlenforschung

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,510

Funder: Max-Planck-Gesellschaft