D3.1. Detailed protocols for each liquid biopsy pilot study
Year: 2026
Type: article
Abstract: The primary objective is to define, collect, and harmonize standard operational protocols for the 7 Liquid Biopsy Pilot Studies planned in SPARC. These pilot studies span multiple oncology indications, including more than 11 cancers. Moreover, they are designed to drive the real-world clinical implementation of liquid biopsy across European healthcare systems.To achieve technical rigor and inter-centre comparability across heterogeneous European healthcare settings, WP3 executed a structured operational strategy. This included a baseline survey (M2–M4), a centralized Excel Pilot Monitoring Tool (M8) for real-time tracking of the pilot progress, and a standardized Protocol Template (M9). Together, these tools establish minimum requirements across pre-analytical, analytical, and clinical workflows, directly supporting the progression of each pilot along the Translation Level of Study (TLS) scale.
Institutions: Azienda Ospedaliero-Universitaria Careggi, University of Arkansas at Fayetteville, University of Florence, Fundacio Investigacio Hospital General Universitari De Valencia, Hospital General Universitario De Valencia, Universitat Politècnica de València, Madrid Health Service, Universidad Politécnica de Madrid
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7225425833