Year: 2026
Type: article
Study design: Case Report
Abstract: Connective tissue nevus (CTN) is a benign hamartomatous lesion characterized by the abnormal proliferation or accumulation of dermal connective tissue components such as collagen, elastin, and proteoglycans.Given its heterogeneous clinical presentation, accurate diagnosis remains challenging.Here, we report a rare case of a large, broad-based, exophytic lesion in the groin of a pediatric patient.The lesion featured a dense papillary surface covered by a mildly thickened epidermis.Scattered blood vessels were observed in the dermis of the exophytic component, along with an increase in collagen fibers.These findings were consistent with the diagnosis of CTN.This case represents an uncommon clinical variant of CTN, characterized by clinical and histopathological features resembling those of adnexal and other hamartomatous lesions.Awareness of such presentations is important for accurate diagnosis and to ensure appropriate management.Further histopathological and immunohistochemical evaluations may aid in differentiating CTN from mimics and assessing potential syndromic associations.
Source: Cureus
Institution: The University of Osaka
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: diamond
OpenAlex ID: W7225430345