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Design, Synthesis, and Biological Evaluation of Indolin-2-one Derivatives as Novel Covalent Pan-FGFR Inhibitors for Overcoming Clinical Resistance

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Year: 2026
Type: article
Source: Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.6c02574
Authors: Wenjian Zhu, Jing Guo, Ling Yan, Xiaojing Lin, Xiaojuan Chen, Xiaojuan Song, Wuqing Deng, Yixin Luo, Zhengchao Tu, Yongheng Chen, Jeff B. Smaill, Adam V. Patterson, Xiaoyun Lu
Institutions: Jinan University, University of Auckland, Central South University
Language: English

Topic: Fibroblast Growth Factor Research
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Jinan University, Maurice Wilkins Centre for Molecular Biodiscovery, Changjiang Scholar Program of Chinese Ministry of Education, Basic and Applied Basic Research Foundation of Guangdong Province
OpenAlex ID: W7225452576
FWCI:
Cites: 32
Cited by:
Related to: 10
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