Work

Design, Synthesis, and Evaluation of a Potent NLRP3 Inflammasome Inhibitor with Favorable Pharmacokinetic and Safety Profiles for Chronic Inflammatory Diseases

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c02821

Authors: Haonan Feng, Yichao Kong, Peng Tang, Haoxin Huang, Yutong Li, Wenjing Gu, Yaxia Yuan, Lei Fang, Weiwei Huang, Xiabin Chen, Lei Ma

Institutions: East China University of Science and Technology, Hangzhou Normal University, The University of Texas at San Antonio Health Science Center

Language: English

Topic: Inflammasome and immune disorders

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, National Key Research and Development Program of China

OpenAlex ID: W7225457503

FWCI:

Cites: 50

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Related to: 10