Work

Thyrotoxic Hypokalemic Periodic Paralysis Presenting As Acute Tetraparesis: A Case Report

Year: 2026

Type: article

Abstract: Thyrotoxic hypokalemic periodic paralysis (TPP) is a rare but potentially life-threatening complication of hyperthyroidism, usually associated with Graves' disease.We report the case of a 29-year-old man with acute flaccid tetraparesis associated with severe hypokalemia.Prompt potassium replacement resulted in rapid clinical and biochemical improvement.The diagnosis of TPP was established based on the clinical presentation, the presence of thyrotoxicosis, severe hypokalemia, and rapid clinical improvement following potassium replacement.Awareness of this condition is essential for early diagnosis and appropriate management, as delayed recognition may result in potentially life-threatening complications, including cardiac arrhythmias and respiratory failure.

Source: Cureus

DOI: 10.7759/cureus.119257

Authors: Tânia Pereira da Silva, Joana Rego, Flávia Santos, Carlos Fernandes, Glória Alves

Institution: Unidade Local de Saúde do Alto Ave

Language: English

Topic: Thyroid Disorders and Treatments

Subfield: Endocrinology, Diabetes and Metabolism

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7225459431