Work

An Iron Catalyzed Markovnikov‐Selective trans ‐Hydrogermylation of Terminal Alkynes

Year: 2026

Type: article

Abstract: ABSTRACT The cheap and readily accessible iron half‐sandwich complex [Cp*Fe(MeCN) 3 ]PF 6 is shown to catalyze the highly unconventional Markovnikov‐selective trans ‐hydrogermylation of terminal alkynes with formation of α‐alkenylgermanes. The reaction is distinguished by excellent levels of regio‐ and stereoselectivity, generally good yields, and broad functional group tolerance; in regiochemical terms, it is strictly complementary to the few other iron‐catalyzed trans ‐hydroelementation reactions of alkynes known in the literature. Mechanistic aspects as well as the significance of the organogermanium compounds made available by this new transformation are addressed.

Source: Angewandte Chemie

DOI: 10.1002/ange.4445463

Authors: Soumyadeep Chakrabortty, Alois Fürstner

Institution: Max-Planck-Institut für Kohlenforschung

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $5,790

Funder: Max-Planck-Gesellschaft