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Revisiting Carbonyl Reductase Stereocontrol: A Third Pocket Accommodates the E Ring in Podophyllotoxone‐Type Ketone Reduction

Year: 2026

Type: article

Source: Angewandte Chemie

DOI: 10.1002/ange.1437091

Authors: Zhen Meng, Congcong Li, Xiao‐Fan Liu, Ya‐Nan Lai, Hong‐Mei Li, Zhoutong Sun, Ting‐Ting Yao, Ya‐Jie Tang

Institutions: Shandong University, State Key Laboratory of Microbial Technology, Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology, Fudan University

Language: English

Topic: Enzyme Catalysis and Immobilization

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

Funders: National Natural Science Foundation of China, Natural Science Foundation of Shandong Province

OpenAlex ID: W7225462470

FWCI:

Cites: 42

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Related to: 10