Work

Utilization of the Nortropinone Scaffold in the Structure-Guided Design of Potent Inhibitors of Human Cathepsin L and the Chymotrypsin-like Proteases of SARS-CoV-2 and MERS-CoV

Year: 2026

Type: article

Source: ACS Pharmacology & Translational Science

DOI: 10.1021/acsptsci.6c00439

Authors: Pulini S. Ranasinghe, I. Kankanamge Ravindu S. Ilesinghe, Chamandi S. Dampalla, Harry Nhat Nguyen, Zeeshan Azmi, Zoie Liska, John X. Bourget, Dennis J. Howard, Dustin E. Nevonen, Yunjeong Kim, Kevin P. Battaile, Anne Cooper, Adron R. Ung, Hayden A. Thurman, Egor Gusachenko, David K. Johnson, Scott Lovell, Kyeong-Ok Chang, William C. Groutas

Institutions: Wichita State University, Kansas State University, New York Structural Biology Center, University of Kansas

Language: English

Topic: SARS-CoV-2 and COVID-19 Research

Subfield: Infectious Diseases

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Institutes of Health, National Institute on Aging, NIH Office of the Director, National Institute of General Medical Sciences, Biological and Environmental Research

OpenAlex ID: W7225468384

FWCI:

Cites: 80

Cited by:

Related to: 10