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Ciprofloxacin: Chemical Structure, Mechanism of Action, Pharmacokinetics and Clinical Significance

Year: 2026

Type: article

Abstract: This article reviews ciprofloxacin, a synthetic antibacterial agent belonging to the fluoroquinolone class. Its chemical characteristics, antibacterial mechanism, pharmacokinetic properties and clinical significance are discussed. Particular attention is paid to the interaction of ciprofloxacin with bacterial DNA gyrase and topoisomerase IV, mechanisms of antimicrobial resistance, adverse reactions and restrictions on use. Based on scientific publications and official medical sources, the article also examines research into ciprofloxacin derivatives and the importance of responsible antimicrobial use.

Source: Web of Medicine: Journal of Medicine, Practice and Nursing

Authors: Kurbanova M. A., Rustamov Shukhratjon Shavkatjonovich

Institution: Tashkent State Medical University

Language: English

Topic: Antibiotics Pharmacokinetics and Efficacy

Subfield: Pharmacology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7225551320

FWCI:

Cites: 5

Cited by:

Related to: 10