Limb Salvage in Limb-Threatening Necrotizing Fasciitis of the Diabetic Foot: A Case Report.
Year: 2026
Type: article
Abstract: Introduction: Necrotizing fasciitis (NF) is a rapidly progressive soft tissue infection with high morbidity and mortality, especially in patients with diabetes mellitus. Early diagnosis is challenging because initial clinical signs may be subtle, yet timely intervention is critical to prevent limb loss and death. Case Report: We report a 68-year-old male with long-standing type 2 diabetes mellitus and multiple comorbidities who presented with a 1-week history of rapidly progressive left foot pain and swelling extending to the mid-calf. Laboratory investigations revealed marked inflammation, and imaging indicated fascial involvement. The patient underwent multiple surgical debridements, broad-spectrum intravenous antibiotics, strict glycemic control, limb off-loading, tibial angioplasty to optimize perfusion, and advanced wound care including negative pressure wound therapy and reconstructive procedures. Progressive healing was achieved without major amputation. Conclusion: Limb salvage remains feasible in selected diabetic patients with limb-threatening NF when early recognition, aggressive surgical management, vascular optimization, metabolic control, and coordinated multidisciplinary care are implemented.
Source: PubMed
Language: English
Subfield: Infectious Diseases
Field: Medicine
Domain: Health Sciences
Open Access status: green
OpenAlex ID: W7225580420