Real-World Evidence for Clinical Adoption of a Crosslinked Hyaluronic Acid Dermal Filler
Year: 2026
Type: article
Abstract: BACKGROUND Conventional clinical study results may not always translate to meaningful real-world outcomes due to strict patient selection and rigorous study design. OBJECTIVE To evaluate real-world clinical experience with use of a crosslinked hyaluronic acid filler containing 0.3% lidocaine. METHODS A survey was developed containing multiple choice and open-answer questions regarding experience with the crosslinked hyaluronic acid filler (OSM) including syringe characteristics, injection procedures, treatment appearance outcomes, patient satisfaction, and practitioner adoption. RESULTS Overall, 394 unique respondents from 317 different aesthetic practices responded to the survey 611 times. A total of 1,517 injections were administered with the most common injection areas being the nasolabial folds, midface, and the labiomental and prejowl sulci. In total, 81.3% (497/611) reported the extrusion force was “Good” or “Very Good” while 85.6% (523/611) reported the syringe was “Easy” or “Very Easy” to use during the injection procedure. A total of 92.6% (566/611) felt the areas of injection looked “Natural” or “Very Natural” after administration. In total, 92.0% (562/611) believe OSM complements current aesthetic treatment options. CONCLUSION In real-world clinical practice, OSM demonstrated high levels of clinician satisfaction. Overall, this study showcases the importance of real-world evidence generation when making aesthetic product adoption decisions.
Source: Dermatologic Surgery
Language: English
Subfield: Dermatology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7225616235