Data on the structure of memory in the protobiotic environment and up to the present day: A census of hidden hysteretic memory in the SABIO-RK database
Year: 2026
Type: preprint
Abstract: An analysis of the SABIO-RK database (76,780 unique records) for documented evidence of hysteresis and slow memory, with and without direct mention of the term, relying solely on the characteristics of the phenomenon in cells/enzymes. The term "hysteretic" is present in only 23 records (bibliographic fields only); the terms "hysteresis", "memory", and "lag phase" are effectively absent. Yet the phenomenon is clearly present under neutral names: 62 records (0.08%) describe slow-binding and biphasic kinetics; the database's dictionary of 194 kinetic-law types contains no term for memory, while within typed records the constants of slow transitions are extracted: the relaxation time spectrum τ = (k₅+k₆)⁻¹ with measured times from 8.7 seconds to 45.5 minutes, indicating a two-phase character of the processes, the second of which is the so-called "memory" or hysteresis. In other words, memory as a phenomenon is documented in the database; the name of memory is not. This work corrects this methodological shortcoming.
Author: Borodin, Oleg
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7225621614
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