Work

Engineering yeast for anticancer drug biosynthesis

Year: 2026

Type: article

Abstract: In a recently published Science article, S hen et al. established a modular yeast platform for the de novo biosynthesis of a direct precursor of etoposide and teniposide from glucose. This advance provides unprecedented perspectives for a sustainable supply chain for these important anticancer drugs.

Source: Cell Discovery

DOI: 10.1038/s41421-026-00937-x

Authors: Nicolas Gautron, Nicolas Papon, Vincent Courdavault

Institutions: Université de Tours, Biomolécules et Biotechnologies Végétales, Université d'Angers

Language: English

Topic: Microbial Metabolic Engineering and Bioproduction

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,590

OpenAlex ID: W7225621619