Work

Successful Thromboembolectomy for PTE in an Adolescent Patient With Catastrophic APS and SLE

Year: 2026

Type: article

Abstract: In a 14-year-old with antiphospholipid syndrome (APS) and lupus anticoagulant, improper switching from warfarin and low-dose aspirin to rivaroxaban led to life-threatening recurrent thrombosis, pulmonary embolism, and pulmonary hypertension. Prompt return to standard anticoagulation plus immunosuppression stabilized the condition. This case underscores that DOACs are contraindicated in high-risk APS.

Source: Clinical Case Reports

DOI: 10.1002/ccr3.73911

Authors: Azadeh Zeinab Mirzaee, Bita Paknejad, Aziz Eghbali, Reza Shiari, Niku Rahimi Afzal

Institutions: Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Iran University of Medical Sciences

Language: English

Topic: Systemic Lupus Erythematosus Research

Subfield: Rheumatology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,820