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Chiral isolation and absolute configuration of (+)- and (−)-desyunnane A and melissifoliane B, two homogentisic acid derivatives from Desmos yunnanensis

Year: 2026

Type: article

Abstract: A previously unreported homogentisic acid derivative (1, desyunnane A) and a known analogue (2, melissifoliane B) were isolated from the branches and leaves of Desmos yunnanensis. Their structures were determined by NMR analysis combined with quantum chemical calculations. Melissifoliane B displayed marginal antifungal activity against Cryptococcus neoformans with an MIC of 128 μg/mL.

Source: Figshare

DOI: 10.6084/m9.figshare.34970365

Authors: Tiantian Wang, Yaping Guo, Tingliang Liu, Zhiying Liu, Shuyun Wang, Yan Wu

Language: English

Topic: Phytochemistry and Biological Activities

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7225752801

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