Mouse Brain Processing for Laser Capture Microdissection (LCM) of Catecholaminergic Brain Regions v1
Year: 2026
Type: preprint
Abstract: This protocol describes the preparation of mouse brain tissue for laser capture microdissection (LCM) of catecholaminergic brain regions including the substantia nigra (SN), ventral tegmental area (VTA), and locus coeruleus (LC).The procedure preserves RNA integrity for downstream transcriptomic analyses including microarrays and qPCR. The protocol was optimized for the study of neuromelanin-containing transgenic mice and wild-type controls.
Authors: Nuria Peñuelas, Ariadna Laguna, Miquel Vila
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W7225780314
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