Work

Thermodynamically Guided CRISPR Spacer Optimization: Strategy-Dependent Off-Target Trade-Offs

Year: 2026

Type: article

Source: Journal of Chemical Information and Modeling

DOI: 10.1021/acs.jcim.6c03063

Authors: Arsenii Kechin, Anastasia Vepreva, Ivan Dubrovsky, Polina Reshetnyak, Andrei Dmitrenko, Nikolay Nikitin, Nikita Serov

Institution: ITMO University

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W7225780747

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Cites: 30

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