Real-world treatment patterns and clinical outcomes in relapsed/refractory multiple myeloma across Asia: a multicenter Asian Myeloma Network study (AMN010)
Year: 2026
Type: article
Abstract: Despite significant therapeutic advances, most patients with multiple myeloma (MM) eventually relapse and require successive lines of therapy, with progressively shorter remissions and increasing drug refractoriness [ 1 , 2 ]. Treatment patterns and outcomes of relapsed/refractory MM (RRMM) patients in Asia differ substantially from those reported in Western populations due to differences in drug availability, reimbursement, healthcare infrastructure, access to clinical trials, patient and carer preferences [ 3 ], and potentially disease biology [ 4 ]. Despite these important differences, real-world data describing treatment sequencing and outcomes across Asia remain limited. We therefore conducted a multinational and multiregional Asian Myeloma Network (AMN) study to characterize real-world treatment patterns and clinical outcomes in MM patients receiving second line (2 L), third line (3 L), and fourth line (4 L) therapy, to provide a benchmark for RRMM treatment management across Asia.
Source: Blood Cancer Journal
Authors: Melinda SY Tan, Kye Ling Wong, Cinnie Soekojo, Chandramouli Nagarajan, Sarah Burkhill, Xinhua Li, Ho-Jin Shin, Jong Heon Jung, Yeung-Chul Mun, Ho-Young Yhim, Jae Hoon Lee, Ling Cao, Tadao Ishida, Chihiro Shimazaki, Makoto Sasaki, Hiroyuki Takamatsu, Shinsuke Iida, Hirono Iriuchishima, Shuji Ozaki, Karen Tang, Jeffrey Huang, Jerry Teng, Cheng-Shyong Chang, Changki Min, Wenming Chen, Hiroshi Handa, Kihyun Kim, Priti Bahety, Juan Du, Wee Joo Chng
Institutions: Singapore General Hospital, National Cancer Centre Singapore, National University Cancer Institute, Singapore, Singapore Clinical Research Institute, Pusan National University Hospital, National Cancer Center, Ewha Womans University Mokdong Hospital, Jeonbuk National University Hospital, Gachon University Gil Medical Center, Tan Tock Seng Hospital, Japanese Red Cross Medical Center, Kyoto Kuramaguchi Medical Center, Juntendo University Hospital, Kanazawa University Hospital, Nagoya City University Hospital, Okinawa Miyako Hospital, Kasukabe Medical Center, Itabashi Chuo Medical Center, Tokushima Prefectural Central Hospital, Queen Mary Hospital, University of Hong Kong, National Taiwan University Hospital, Taichung Veterans General Hospital, Chang Bing Show Chwan Memorial Hospital, The Catholic University of Korea Seoul St. Mary's Hospital, Beijing Chao-Yang Hospital, Capital Medical University, Gunma University, Samsung Medical Center, Shanghai Changzheng Hospital
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: gold
Estimated APC paid: $5,290
OpenAlex ID: W7225804417