Work

Generative AI-Driven Interpolation of Cross-Family Kinase Space: Discovery of Dual-Targeting Degraders of IRAK4 and TYK2

Year: 2026

Type: article

Source: Journal of Medicinal Chemistry

DOI: 10.1021/acs.jmedchem.6c00913

Authors: Meng Fang, Zhouli Yang, Jiamu Cai, Yi Cai, Chaoguo Cao, Tianlei Li, Chao Zhang, Xiuyun Sun, Yu Rao

Institutions: Tsinghua University, Soochow University, Changping Laboratory

Language: English

Topic: Computational Drug Discovery Methods

Subfield: Drug Discovery

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

Open Access status: closed

OpenAlex ID: W7225807897

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Cites: 33

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